Publications
- Rapid identification of human muscle disease with fibre optic Raman spectroscopy. James J.P. Alix, Maria Plesia, Gavin R. Lloyd, Alexander P. Dudgeon, Catherine A. Kendall, Channa Hewamadduma, Marios Hadjivassiliou, Christopher J. McDermott, Grainne S. Gorman, Robert W. Taylor, Pamela J. Shaw, John C.C. Day. Analyst, 2022,147, 2533-2540 https://doi.org/10.1039/D1AN01932E
- Fiber optic Raman spectroscopy for the evaluation of disease state in Duchenne muscular dystrophy: An assessment using the mdx model and human muscle. James J.P. Alix, Maria Plesia, Sarah A. Hool, Ian Coldicott, Catherine A. Kendall, Pamela J. Shaw, Richard J Mead, John C Day. Muscle & Nerve. Volume, issue 3, pages 362-369, September 2022. https://doi.org/10.1002/mus.27671
- The application of Raman Spectroscopy to the diagnosis of mitochondrial muscle disease: A preliminary comparison between fibre optic probe and microscope formats. James J. P. Alix; Maria Plesia; Gavin R. Lloyd; Alexander P. Dudgeon; Catherine A. Kendall; Christopher J. McDermott; Gráinne S. Gorman; Robert W. Taylor; Pamela J. Shaw; John C. Day. Journal of Raman Spectroscopy. Volume 53.Issue 2. Pages 167-322. February 2022. DOI: https://doi.org/10.1002/jrs.6273
- Rapid identification of human muscle disease with fibre optic Raman spectroscopy. James J. P. Alix; Maria Plesia; Gavin R. Lloyd; Alexander P. Dudgeon; Catherine A. Kendall; Channa Hewamadduma; Marios Hadjivassiliou; Christopher J. McDermott; Gráinne S. Gorman; Robert W. Taylor et al. Analyst, 2022,147, 2533-2540. DOI: 10.1039/D1AN01932E
- Non‐negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue. James J. P. Alix; Maria Plesia; Chlöe N. Schooling; Alexander P. Dudgeon; Catherine A. Kendall; Visakan Kadirkamanathan; Christopher J. McDermott; Gráinne S. Gorman; Robert W. Taylor; Richard J. Mead et al. Journal of Raman Spectroscopy. Volume 54. Issue 3. Pages 233-250. March 2023. DOI: 10.1002/jrs.6480
- Identification of mitochondrial disease from muscle biopsies using Raman spectroscopy: a preliminary comparison between fibre optic probe and microscope formats. James J.P. Alix, Maria Plesia, Gavin R. Lloyd, Alex Dudgeon, Catherine A. Kendall, Christopher J. McDermott, Gráinne S. Gorman, Robert W. Taylor, Pamela J. Shaw, John C. Day Journal of Raman Spectroscopy 2021 https://doi.org/10.1002/jrs.6273
- Love, S.B., Kilanowski, A., Yorke-Edwards, V. et al. Use of routinely collected health data in randomised clinical trials: comparison of trial-specific death data in the BOSS trial with NHS Digital data. Trials 22, 654 (2021). https://doi.org/10.1186/s13063-021-05613-x
- In vivo fibre optic Raman spectroscopy of muscle in preclinical models of amyotrophic lateral sclerosis and Duchenne muscular dystrophy. Maria Plesia, Oliver A. Stevens, Gavin R. Lloyd, Catherine A. Kendall, Ian Coldicott, Aneurin J. Kennerley, Gaynor Miller, Pamela J. Shaw, Richard J. Mead, John C. C. Day, James J.P. ACS Chemical Neuroscience 2021 May 19;12(10):1768-1776. doi: 10.1021/acschemneuro.0c00794.
- Raman Spectroscopy: Twenty-five Years of Concept to Clinical application for Early Diagnosis of Pre-cancer In Barrett’s Oesophagus. M S Noor Mohamed, A Dudgeon, E Upchurch, O J Old, A Pavlou, L M Almond, G R Lloyd, M Isabelle, J Hutchings, C Kendall, J Day, N Stone, H Barr. Asian Journal of Physics 2021 30(2) 273-280
- Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study Guo, Shuxia; Beleites, Claudia; Neugebauer, Ute;…. Kendall, Catherine;….Popp, Juergen; Bocklitz, Thomas Analytical Chemistry 2020 92 15745-15756 http://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c02696
- Automated cytological detection of Barrett's neoplasia with infrared spectroscopy. Old, O.; Lloyd, G.; Isabelle, M.; Almond, L M.; Kendall, C.; Baxter, K.; Shepherd, N.; Shore, A.; Stone, N.; and Barr, H. Journal of Gastroenterology, 53(2): 227–235. (2018). doi: 10.1007/s00535-017-1344-z
- The Role of Raman Spectroscopy in Differentiating Grades of Dysplasia in Barrett's Oesophagus: Is It Currently Good Enough? Upchurch E, Isabelle M, Lloyd GR, Kendall C, Stone N, et al. (2018) Int J Exp Spectroscopic Tech 3:013. https://www.vibgyorpublishers.org/content/ijest/fulltext.php?aid=ijest-3-013
- An update on the use of Raman spectroscopy in molecular cancer diagnostics: current challenges and further prospects. Emma Upchurch, Martin Isabelle, Gavin Rhys Lloyd, Catherine Kendall & Hugh Barr (2018). Expert Review of Molecular Diagnostics, DOI:10.1080/14737159.2018.1439739
- Developing Raman spectroscopy as a diagnostic tool for label-free antigen detection. Lewis, A. T; Gaifulina, R.; Guppy, N. J; Isabelle, M.; Dorney, J.; Lloyd, G. R; Rodriguez-Justo, M.; Kendall, C.; Stone, N.; and Thomas, G. M. Journal of biophotonics, 11(2): e201700028. 2018.
- Automated cytological detection of Barrett's neoplasia with infrared spectroscopy. Old, O.; Lloyd, G.; Isabelle, M.; Almond, L M.; Kendall, C.; Baxter, K.; Shepherd, N.; Shore, A.; Stone, N.; and Barr, H. Journal of Gastroenterology, 53(2): 227–235. 2018. DOI:10.1007/s00535-017-1344-z
- The Role of Raman Spectroscopy in Differentiating Grades of Dysplasia in Barrett's Oesophagus: Is It Currently Good Enough?. Upchurch E, Isabelle M, Lloyd GR, Kendall C, Stone N, et al. (2018) Int J Exp Spectroscopic Tech 3:013. Link
- An update on the use of Raman spectroscopy in molecular cancer diagnostics: current challenges and further prospects, Emma Upchurch, Martin Isabelle, Gavin Rhys Lloyd, Catherine Kendall & Hugh Barr (2018). Expert Review of Molecular Diagnostics, DOI:10.1080/14737159.2018.1439739
- Developing Raman spectroscopy as a diagnostic tool for label-free antigen detection. Lewis, A. T; Gaifulina, R.; Guppy, N. J; Isabelle, M.; Dorney, J.; Lloyd, G. R; Rodriguez-Justo, M.; Kendall, C.; Stone, N.; and Thomas, G. M Journal of Biophotonics, 11(2): e201700028. 2018. DOI:10.1002/jbio.201700028
- Elemental vs. phase composition of breast calcifications, Scott R, Kendall C, Stone N, Rogers K. Sci Rep, 7(1), 136, 2017. DOI:10.1038/s41598-017-00183-y
- Elemental vs. phase composition of breast calcifications, Scott R, Kendall C, Stone N, Rogers K. Sci Rep, 7(1), 136, 2017. DOI:10.1038/s41598-017-00183-yDevelopments in optical imaging for gastrointestinal surgery, E Upchurch, S Griffiths, G Rhys Lloyd, M Isabelle, CKendall, H Barr Future Oncology, 13:26, 2363-2382, 2017
- Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus. O J Old, G R Lloyd, J Nallala, M Isabelle, L M Almond, N A Shepherd, C A Kendall, A C Shore, H Barr, N Stone. The Analyst, 142(8): 1227–1234. 2017, DOI:10.1039/c6an01871h
- Detection of dysplasia in Barrett’s oesophagus: Are there impending optical and spectroscopic solutions? Upchurch E, Old OJ, Lloyd GR, Isabelle M, Kendall C1, Shetty G, Pavlou A, Shepherd N, Barr H. Gastroenterology, Hepatology and Endoscopy 1(3): 61-67 2016. DOI:10.15761/GHE.1000115
- Nallala J, Lloyd GR, Shepherd N, Stone N. (2016) High-resolution FTIR imaging of colon tissues for elucidation of individual cellular and histopathological features, Analyst, volume 141, no. 2, pages 630-639 2016, DOI:10.1039/c5an01871d
- Jayakrupakar Nallala, Gavin R. Lloyd, Catherine Kendall, Hugh Barr, Neil Shepherd, Nick Stone, "Identification of GI cancers utilising rapid mid-infrared spectral imaging", Proc. SPIE 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 970303 (7 March 2016); DOI:10.1117/12.2209363
- Seddon AB, Benson TM, Sujecki S, Abdel-Moneim N, Tang Z, Furniss D, Sojka L, Stone N, Jayakrupakar N, Lloyd GR. (2016) Towards the mid-infrared optical biopsy, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2211584
- Lloyd GR, Nallala J, Stone N. (2016) Investigating the effect of pixel size on high spatial resolution FTIR imaging for detection of colorectal cancer, OPTICAL BIOPSY XIV: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS, volume 9703, DOI:10.1117/12.2210844
- Leanne M. Fullwood, Ingeborg E. Iping Petterson, Alexander P. Dudgeon, Gavin R. Lloyd, Catherine Kendall, Charlie Hall, John C. C. Day, Nick Stone, "Evaluation of a multi-fibre needle Raman probe for tissue analysis", Proc. SPIE 9704, Biomedical Vibrational Spectroscopy 2016: Advances in Research and Industry, 97040G (7 March 2016); DOI:10.1117/12.2230005
- Katherine Lau, Martin Isabelle, Gavin R. Lloyd, Oliver Old, Neil Shepherd, Ian M. Bell, Jennifer Dorney, Aaran Lewis, Riana Gaifulina, Manuel Rodriguez-Justo, Catherine Kendall, Nicholas Stone, Geraint Thomas, David Reece: The road map towards providing a robust Raman spectroscopy-based cancer diagnostic platform and integration into clinic. Proceedings of SPIE - The International Society for Optical Engineering 03/2016; 9704., DOI:10.1117/12.2230007
- Identification of cancer-associated molecular changes in histologically benign vulval disease found in association with vulval squamous cell carcinoma using Fourier transform infrared spectroscopy. Jonathan Frost, Linmarie Ludeman, Kathryn Hillaby, Rob Gornall, Gavin Rhys Lloyd, Catherine Kendall, Angela C Shore, Nick Stone. Analytical methods 11/2016; 8(48)., DOI:10.1039/C6AY03059A
- Relationships between pathology and crystal structure in breast calcifications: an in situ X-ray diffraction study in histological sections. Robert Scott, Nicholas Stone, Catherine Kendall, Kalotina Geraki, Keith Rogers. 09/2016; 2., DOI:10.1038/npjbcancer.2016.29
- Label-free Raman spectroscopic imaging to extract morphological and chemical information from a formalin-fixed, paraffin-embedded rat colon tissue section. Riana Gaifulina, Andrew Thomas Maher, Catherine Kendall, James Nelson, Manuel Rodriguez-Justo, Katherine Lau, Geraint Mark Thomas. International Journal of Experimental Pathology 09/2016; 97(4), DOI:10.1111/iep.12194
- Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells. Aaran T. Lewis, Riana Gaifulina, Martin Isabelle, Jennifer Dorney, Mae L. Woods, Gavin R. Lloyd, Katherine Lau, Manuel Rodriguez‐Justo, Catherine Kendall, Nicholas Stone, Geraint M. Thomas. Journal of Raman Spectroscopy 07/2016; DOI:10.1002/jrs.4980
- Infrared spectroscopy for the biomolecular assessment of vulval intraepithelial neoplasia and lichen sclerosus found in association with squamous cell carcinoma. Jonathan Frost, Linmarie Ludeman, Kathryn Hillaby, Robert Gornall, Gavin Lloyd, Catherine Kendall, Angela C Shore, Nick Stone. British Journal of Obstetrics and Gynaecology 06/2016
- Multi-Centre Raman Spectral Mapping of Oesophageal Cancer Tissues: a study to assess system transferability. Martin Isabelle, Jennifer Dorney, Aaran Lewis, Gavin Rhys Lloyd, Oliver Old, Neil Shepherd, Manuel Rodriguez-Justo, Hugh Barr, Katherine Lau, Ian Bell, Stephanie Ohrel, Geraint Thomas, Nick Stone, Catherine Kendall. Faraday Discussions 06/2016; 187., DOI:10.1039/C5FD00183H
- Katherine Lau, Martin Isabelle, Gavin R. Lloyd, Oliver Old, Neil Shepherd, Ian M. Bell, Jennifer Dorney, Aaran Lewis, Riana Gaifulina, Manuel Rodriguez-Justo, Catherine Kendall, Nicholas Stone, Geraint Thomas, David Reece: The road map towards providing a robust Raman spectroscopy-based cancer diagnostic platform and integration into clinic. Proceedings of SPIE - The International Society for Optical Engineering 03/2016; 9704., DOI:10.1117/12.2230007
- Towards the intra-operative use of Raman spectroscopy in breast cancer—overcoming the effects of theatre lighting. Jonathan D. Horsnell, Catherine Kendall, Nicholas Stone. Lasers in Medical Science 05/2016; 31(6), DOI:10.1007/s10103-016-1959-y
- Raman spectroscopy for medical diagnostics - From in-vitro biofluid assays to in-vivo cancer detection. Kenny Kong, Catherine Kendall, Nick Stone, Ioan Notingher. Advanced Drug Delivery Reviews 2015 DOI:10.1016/j.addr.2015.03.009
- Infrared micro-spectroscopy for cyto-pathological classification of esophageal cells. Douglas Townsend, Miloš Miljković, Benjamin Bird, Kathleen Lenau, Oliver Old, Max Almond, Catherine Kendall, Gavin Lloyd, Neil Shepherd, Hugh Barr, Nick Stonee and Max Diem. Analyst 2014 DOI:10.1039/c4an01884b
- Endoscopic Raman spectroscopy enables objective diagnosis of dysplasia in Barrett's Oesophagus. L.M. Almond, J. Hutchings, G. R. Lloyd, H. Barr, N. Shepherd, J. Day, O. Stevens, S. Sanders, M. Wadley, N. Stone, C. Kendall. Gastrointestinal Endoscopy 2014 79 (1), 37-45; DOI:10.1016/j.gie.2013.05/028
- Raman Spectroscopy and Multivariate Analysis for the Non Invasive Diagnosis of Clinically Inconclusive Vulval Lichen Sclerosus. J. Frost, L. Ludeman, K. Hillaby, R.Gornall, G.R. Lloyd, C. Kendall, A.C.Shore, N.Stone: The Analyst 142(8): 1200-1206. 2017; DOI:10.1039/C6AN02009G